ProSci

SMC2 Antibody

Product Code:
 
PSI-61-428
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-SMC2 Antibody in Jurkat cell line lysates (35ug/lane)
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Western blot analysis of anti-SMC2 Antibody in Jurkat cell line lysates (35ug/lane)

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PSI-61-428-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Structural maintenance of chromosomes protein 2, SMC protein 2, SMC-2, Chromosome-associated protein E, hCAP-E, XCAP-E homolog, SMC2, CAPE, SMC2L1
Application Note:
For WB starting dilution is: 1:1000
Background:
SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Background References:
  • Schmiesing,J.A., Proc. Natl. Acad. Sci. U.S.A. 95 (22), 12906-12911 (1998)
  • Ham,M.F., Cancer Sci. 98 (7), 1041-1047 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SMC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1166-1197 amino acids from the C-terminal region of human SMC2.
NCBI Gene ID #:
10592
NCBI Official Name:
Structural maintenance of chromosomes protein 2
NCBI Official Symbol:
SMC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
136 kDa
Protein Accession #:
O95347
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
O95347
User NOte:
Optimal dilutions for each application to be determined by the researcher.