ProSci

GNLY Antibody

Product Code:
 
PSI-56-835
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

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PSI-56-835-400ul400ul£626.00
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Further Information

Additional Names:
Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Xing, J., et al. J. Immunol. 185(9):5074-5081(2010)
  • Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Yang, C., et al. Int. J. Tuberc. Lung Dis. 13(11):1360-1366(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.
NCBI Gene ID #:
10578
NCBI Official Name:
Granulysin
NCBI Official Symbol:
GNLY
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
P22749
Protein GI Number:
116242500
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P22749
User NOte:
Optimal dilutions for each application to be determined by the researcher.