Further Information
Voltage-gated potassium channel subunit beta-1, K(+) channel subunit beta-1, Kv-beta-1, KCNAB1, KCNA1B
For WB starting dilution is: 1:1000
Potassium channels represent the most complex class of
voltage-gated ion channels from both functional and structural
standpoints. Their diverse functions include regulating
neurotransmitter release, heart rate, insulin secretion, neuronal
excitability, epithelial electrolyte transport, smooth muscle
contraction, and cell volume. Four sequence-related potassium
channel genes - shaker, shaw, shab, and shal - have been identified
in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member includes three distinct
isoforms which are encoded by three alternatively spliced
transcript variants of this gene. These three isoforms are beta
subunits, which form heteromultimeric complex with alpha subunits
and modulate the activity of the pore-forming alpha subunits.
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Decher, N., et al. EMBO J. 27(23):3164-3174(2008)
- Cavalleri, G.L., et al. Lancet Neurol 6(11):970-980(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This KCNAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KCNAB1.
7881
Voltage-gated potassium channel subunit beta-1
KCNAB1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Q14722
18202500
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience
Q14722
Optimal dilutions for each application to be determined by the researcher.