ProSci

ZFYVE27 Antibody

Product Code:
 
PSI-58-971
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).

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PSI-58-971-400ul400ul£626.00
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Further Information

Additional Names:
Protrudin, Zinc finger FYVE domain-containing protein 27, ZFYVE27
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
Background References:
  • Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)
  • Martignoni, M., et al. Am. J. Hum. Genet. 83(1):127-128(2008)
  • Shirane, M., et al. Science 314(5800):818-821(2006)
  • Mannan, A.U., et al. Am. J. Hum. Genet. 79(2):351-357(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.
NCBI Gene ID #:
118813
NCBI Official Name:
Protrudin
NCBI Official Symbol:
ZFYVE27
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q5T4F4
Protein GI Number:
74744927
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q5T4F4
User NOte:
Optimal dilutions for each application to be determined by the researcher.