Further Information
5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, S12, Serotonin 1D beta receptor, 5-HT-1D-beta, Serotonin receptor 1B, HTR1B, HTR1DB
For WB starting dilution is: 1:1000
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kiezebrink, K., et al. World J. Biol. Psychiatry 11(6):824-833(2010) Mekli, K., et al. Eur Neuropsychopharmacol (2010) In pressPinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010)Cross, D.S., et al. BMC Genet. 11, 51 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Pig, Rabbit
This HTR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human HTR1B.
3351
5-hydroxytryptamine receptor 1B
HTR1B
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
P28222
112821
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Neuroscience,Growth Factor
P28222
Optimal dilutions for each application to be determined by the researcher.