ProSci

ATP1A3 Antibody

Product Code:
 
PSI-60-827
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-60-827-400ul400ul£626.00
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Further Information

Additional Names:
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3, ATP1A3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit.
Background References:
  • Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010)
  • Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010)
  • Hauck, C., et al. Eur. J. Pharmacol. 622 (1-3), 7-14 (2009) :
  • Blanco-Arias, P., et al. Hum. Mol. Genet. 18(13):2370-2377(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen:
This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.
NCBI Gene ID #:
478
NCBI Official Name:
Sodium/potassium-transporting ATPase subunit alpha-3
NCBI Official Symbol:
ATP1A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
P13637
Protein GI Number:
116241260
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
P13637
User NOte:
Optimal dilutions for each application to be determined by the researcher.