ProSci

NPL Antibody

Product Code:
 
PSI-60-193
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in U251 cell line lysates (35ug/lane).
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Western blot analysis in U251 cell line lysates (35ug/lane).

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PSI-60-193-400ul400ul£626.00
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Further Information

Additional Names:
N-acetylneuraminate lyase, NALase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialate-pyruvate lyase, Sialic acid aldolase, Sialic acid lyase, NPL, C1orf13
Application Note:
For WB starting dilution is: 1:1000
Background:
N-acetylneuraminate pyruvate lyase (EC 4.1.3.3) controls the cellular concentration of sialic acid by catalyzing the conversion of sialic acid into acylmannosamines and pyruvate (Wu et al., 2005 [PubMed 16147865]).
Background References:
  • Chu, H.Y., et al.Mol Model 15(3):323-328(2009)
  • Wu, M., et al. DNA Seq. 16(2):137-142(2005)
  • Traving, C., et al. Eur. J. Biochem. 268(24):6473-6486(2001)
  • Sood, R., et al. Genomics 73(2):211-222(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human NPL.
NCBI Gene ID #:
80896
NCBI Official Name:
N-acetylneuraminate lyase
NCBI Official Symbol:
NPL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q9BXD5
Protein GI Number:
74752428
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9BXD5
User NOte:
Optimal dilutions for each application to be determined by the researcher.