ProSci

MRI1 Antibody

Product Code:
 
PSI-61-260
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:8000 dilution Lane 1: HL-60 whole cell lysate Lane 2: PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:8000 dilution Lane 1: HL-60 whole cell lysate Lane 2: PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-61-260-200ul200ul£626.00
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Further Information

Additional Names:
Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, M1Pi {ECO:0000255|HAMAP-Rule:MF_03119}, MTR-1-P isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, 5.3.1.23 {ECO:0000255|HAMAP-Rule:MF_03119}, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255|HAMAP-Rule:MF_03119}, MRI1 {ECO:0000255|HAMAP-Rule:MF_03119}, MRDI
Application Note:
For WB starting dilution is: 1:8000
Background:
Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Background References:
  • Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
  • Bechtel S.,et al.BMC Genomics 8:399-399(2007).
  • Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
  • Kabuyama Y.,et al.Mol. Cell. Proteomics 8:2308-2320(2009).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human MRI1.
NCBI Gene ID #:
84245
NCBI Official Name:
Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}
NCBI Official Symbol:
MRI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9BV20
Protein GI Number:
74733279
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9BV20
User NOte:
Optimal dilutions for each application to be determined by the researcher.