ProSci

MINPP1 Antibody

Product Code:
 
PSI-57-939
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

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PSI-57-939-400ul400ul£626.00
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Further Information

Additional Names:
Multiple inositol polyphosphate phosphatase 1,3-bisphosphoglycerate 3-phosphatase,3-BPG phosphatase, Inositol (1,5)-tetrakisphosphate 3-phosphatase, Ins(1,5)P(4) 3-phosphatase, MINPP1, MIPP
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.
Background References:
  • Newman, A.B., et al. J. Gerontol.Biol. Sci. Med. Sci. 65(5):478-487(2010)
  • Cho, J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(16):5998-6003(2008)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human MINPP1.
NCBI Gene ID #:
9562
NCBI Official Name:
Multiple inositol polyphosphate phosphatase 1
NCBI Official Symbol:
MINPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9UNW1
Protein GI Number:
68565617
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UNW1
User NOte:
Optimal dilutions for each application to be determined by the researcher.