ProSci

SNUPN Antibody

Product Code:
 
PSI-58-602
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A375 cell line lysates (35ug/lane).
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Western blot analysis in A375 cell line lysates (35ug/lane).

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PSI-58-602-400ul400ul£626.00
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Further Information

Additional Names:
Snurportin-1, RNA U transporter 1, SNUPN, RNUT1, SPN1
Application Note:
For WB starting dilution is: 1:1000
Background:
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Background References:
  • Goette, M., et al. Biophys. J. 97(2):581-589(2009)
  • Monecke, T., et al. Science 324(5930):1087-1091(2009)
  • Ospina, J.K., et al. Mol. Biol. Cell 16(10):4660-4671(2005)
  • Stelzl, U., et al. Cell 122(6):957-968(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SNUPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human SNUPN.
NCBI Gene ID #:
10073
NCBI Official Name:
Snurportin-1
NCBI Official Symbol:
SNUPN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
O95149
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O95149
User NOte:
Optimal dilutions for each application to be determined by the researcher.