ProSci

NHEJ1 Antibody

Product Code:
 
PSI-57-772
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-57-772-400ul400ul£626.00
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Further Information

Additional Names:
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor, NHEJ1, XLF
Application Note:
For WB starting dilution is: 1:1000
Background:
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Background References:
  • Malivert, L., et al. J. Biol. Chem. 285(34):26475-26483(2010)
  • Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
  • Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
  • Andres, S.N., et al. Mol. Cell 28(6):1093-1101(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NHEJ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-296 amino acids from the C-terminal region of human NHEJ1.
NCBI Gene ID #:
79840
NCBI Official Name:
Non-homologous end-joining factor 1
NCBI Official Symbol:
NHEJ1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q9H9Q4
Protein GI Number:
74734059
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H9Q4
User NOte:
Optimal dilutions for each application to be determined by the researcher.