ProSci

Mouse Acvr2b Antibody

Product Code:
 
PSI-57-347
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:1000 dilution Lane 1: mouse kidney lysate Lane 2: mouse skeletal muscle lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution Lane 1: mouse kidney lysate Lane 2: mouse skeletal muscle lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
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Western Blot at 1:1000 dilution Lane 1: mouse kidney lysate Lane 2: mouse skeletal muscle lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution Lane 1: mouse kidney lysate Lane 2: mouse skeletal muscle lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).

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PSI-57-347-400ul400ul£626.00
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Further Information

Additional Names:
Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB, Acvr2b
Application Note:
For WB starting dilution is: 1:1000
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Background References:
  • Natale, D.R., et al. Dev. Biol. 335(1):120-131(2009)
  • Gamer, L.W., et al. Dev. Dyn. 238(9):2374-2381(2009)
  • Yamamoto, M., et al. J. Cell Biol. 184(2):323-334(2009)
  • Morita, S., et al. PLoS ONE(1), E4212 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Acvr2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of mouse Acvr2b.
NCBI Gene ID #:
11481
NCBI Official Name:
Activin receptor type-2B
NCBI Official Symbol:
Acvr2b
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P27040
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P27040
User NOte:
Optimal dilutions for each application to be determined by the researcher.