NSJ Bioreagents

alpha 2a Adrenergic Receptor Antibody

Product Code:
 
NSJ-R30168
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of alpha 2a Adrenergic Receptor antibody and Lane 1: rat testis; 2: rat brain; 3: MCF-7; 4: MM453; 5: SMMC-7721; 6: HeLa; 7: COLO320 cell lysate
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Western blot testing of alpha 2a Adrenergic Receptor antibody and Lane 1: rat testis; 2: rat brain; 3: MCF-7; 4: MM453; 5: SMMC-7721; 6: HeLa; 7: COLO320 cell lysate

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NSJ-R30168-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the alpha 2a Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Alpha-2-adrenergic receptor(ADRA2), also known as platelet type adrenoceptor alpha-2A ,is a member of G protein-coupled receptor superfamily. This gene, which can identify a DraI RFLP of the ADRAR gene, mapped to 10q23-q25, is found in the distal region of mouse chromosome 19 and abundantly expressed in giant cell. ADRA2 acts a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. It has 3 highly homologous subtypes: ADRA2A; ADRA2B and ADRA2C. Studies in mouse suggested that both the ADRA2A and ADRA2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. ADRA2A receptors inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human alpha 2a Adrenergic Receptor (FGYCNSSLNPVIYTIFNH) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody.
Limitation:
This alpha 2a Adrenergic Receptor antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P08913