NSJ Bioreagents

LOX Antibody / Lysyl Oxidase

Product Code:
 
NSJ-R32045
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the LOX antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of rat 1) lung, 2) kidney, 3) thymus, and 4) mouse kidney lysate with LOX antibody. Expected molecular weight: ~47 kDa (unprocessed/unmodified), ~50 kDa (glycosylated), ~32 kDa (processed form).
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Western blot testing of rat 1) lung, 2) kidney, 3) thymus, and 4) mouse kidney lysate with LOX antibody. Expected molecular weight: ~47 kDa (unprocessed/unmodified), ~50 kDa (glycosylated), ~32 kDa (processed form).

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NSJ-R32045-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the LOX antibody should be determined by the researcher.
Description:
Lysyl oxidase, also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids AEENCLASTAYRADVRDYDHRVLLRFPQR of human Lysyl Oxidase were used as the immunogen for the LOX antibody.
Limitation:
This LOX antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P28300