NSJ Bioreagents

RIP1 Antibody

Product Code:
 
NSJ-R31540
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the RIP1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 3
Western blot testing of RIP1 antibody and Lane 1: Jurkat; 2: 22RV1; 3: MCF-7; 4: HeLa; 5: A549. Expected/observed size ~76KD
2 / 3
Western blot testing of RIP1 antibody and recombinant human protein (0.5ng)
3 / 3
Western blot testing of human 1) PANC1, 2) SKOV-3 and 3) HeLa cell lysate (50ug/lane) with RIP1 antibody at 0.5ug/ml. Predicted molecular weight ~76 kDa.
❮❯

Western blot testing of RIP1 antibody and Lane 1: Jurkat; 2: 22RV1; 3: MCF-7; 4: HeLa; 5: A549. Expected/observed size ~76KD
Western blot testing of RIP1 antibody and recombinant human protein (0.5ng)
Western blot testing of human 1) PANC1, 2) SKOV-3 and 3) HeLa cell lysate (50ug/lane) with RIP1 antibody at 0.5ug/ml. Predicted molecular weight ~76 kDa.

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-R31540-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the RIP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
RIPK1, also known as RIP or RIP1, is an enzyme that in humans is encoded by the RIPK1 gene. It is mapped to 6p25.2. RIPK1 is a key signaling molecule in the programmed necrosis pathway, which plays important roles in development, tissue damage response, and antiviral immunity. RIPK1 is known to have function in a variety of cellular pathways including the NF-kB pathway and programmed necrotic cell death (necroptosis). The kinase domain, while important for necroptotic (programmed necrotic) functions, it appears dispensable for other lethal, as well as pro-survival roles. Also, proteolytic processing of RIPk1, through both caspase-dependent and -independent mechanisms, triggers lethality that is dependent on the generation of one or more specific C-terminal cleavage product(s) of RIPk1 upon stress.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
8737
Immunogen:
Human partial recombinant protein (AA 316-671) was used as the immunogen for this RIP1 antibody.
Limitation:
This RIP1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human