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Camelid Single Domain Antibodies (sdAbs), also known as nanobodies, have emerged as powerful tools in immunology and molecular biology. CD8A, a vital cell surface glycoprotein in immune responses, has become a focus of research and diagnostics. Derived from camelids, these sdAbs offer advantages such as a small size for precise targeting, stability in extreme conditions, and unique binding capabilities.
Documents
Antibodies
Abnova Corporation
Abnova offers Camelid Single Domain Antibody Service for production of target-specific sdAb from naïve camelid VHH library. By using the advanced naïve camelid VHH library screening technology, they screen the library and isolate the sdAb clones for your required antigens. Positive clones are sequenced and validated by ELISA. The selected clones will then be introduced into HEK293 expression vector or E. coli expression vector for transient and scalable sdAb production for many downstream applications.
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Service
Abnova Corporation
Abnova camelid single domain antibodies (sdAbs) derived from alpacas or llamas with great penetrability and affinity to recognize difficult epitopes. The product lines include FluoTag-Q, FluoTag-X2 and FluoTag-X4, featuring different number of sdAb and coupled fluorophore. In FluoTag-Q series, each fluorophore is conjugated to exactly one sdAb. The FluoTag-X2 series contains two fluorophores coupled with one sdAb. In terms of FluoTag-X4, it is a mix of 2 sdAbs that can bind simultaneously with the target molecule, and each sdAb is coupled with 2 fluorophores.
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Antibodies
Abnova Corporation
iXCells provides products to accelerate drug discovery, development and translation for nervous system disorders.
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Neuroscience
iXCells Biotechnologies
The term "adjuvant" derives from adjuvare, meaning to assist. Any material that increases the humoral and/or cellular immune response of an antigen is considered as an adjuvant and it is said to be immunogenic. A multitude of adjuvants of extremely diverse origin exist. Two of the most distinguished adjuvant types are the immune-stimulating agents and the "vaccine-carriers". The immune-stimulating agents activate the immune cells directly by binding to different receptors. While the vaccine carriers contain the antigen and are able to incorporate it into the immune system in different manners. However, vehicles often have their own immunostimulatory properties, simply because they constitute foreign bodies.
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Immunology
Oz Biosciences
Magnetofection™ was developed to gather, in one convenient system, the advantages of the popular biochemical (cationic lipids or polymers) and physical transfection methods (electroporation, gene gun) while overcoming their respective limitations such as low efficiency, toxicity, and difficulty in handling. Magnetofection can be defined as the delivery of nucleic acids, either naked or packaged (in complexes with lipids or polymers, and viruses), using magnetic nanoparticles (MNP) under the guidance of an external magnetic field.
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Transfection
Oz Biosciences
RNA can suffer degradation when not handled, stored, or used properly. In order to assess how stable OZ Biosciences mRNA is, they have tested a randomly chosen RNA from their catalogue, Tomato RNA, and submitted it to several freeze/thaw cycles as well as mid-term storage at room temperature (RT).
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RNA
Oz Biosciences
Leadgenes manufacturing capabilities include the production of a broad array of high-quality recombinant proteins, inclusive of a comprehensive human cytokine panel designed for immunology and cancer research. In addition, they also provide GMP-grade proteins from their ISO 13485 certified facility. These GMP-grade proteins are ideally suited for studies involving ex vivo cellular expansion, polarisation, or differentiation.
Videos
Proteins
LeadGene Biomedical
Leadgene Biomedical is at the forefront of recombinant proteins and antibodies production, setting a benchmark in the industry. They take pride in their ISO13485 and QMS (GMP) certifications, symbols of their unwavering commitment to quality and compliance. Their portfolio includes a wide range of reagents and ancillary materials vital for protein development, molecular biology, and immunology studies. This encompasses protease, enzymes, DNA amplification reagents, and cytokines. With a relentless focus on innovation and a passion for excellence, they strive to provide their clients with unparalleled products and services, forging a pathway to discoveries and breakthroughs in biomedical science. Trust in Leadgene, where cutting-edge technology meets quality and integrity.
Videos
Catalogue
LeadGene Biomedical
Leadgene Biomedical, a premier protein and antibody manufacturer, specialises in In Vitro Diagnostic (IVD) assays and provides raw materials, contract research, and cell line development. Leadgenes indoxyl sulfate ELISA kit for chronic kidney disease diagnosis is famous for its highly sensitive characteristic, cost-effectiveness, and verified through CE-IVD certification. Their innovative lyophilisation technology allows room-temperature storage and shipping of IVD assay reagents. Adhering to ISO 13485 and GMP guidelines, Leadgene produces a range of materials in state-of-the-art facilities. Partnering with Leadgene offers a top-tier choice for assay development and protein production.
Videos
Catalogue
LeadGene Biomedical
iXCells offers a diverse range of hepatic cell products designed to cater to your specific needs. Whether youre focused on drug metabolism studies, liver disease research, or toxicology assessments, their catalogue of cells is tailored to accelerate your scientific discoveries.
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Primary Cells
iXCells Biotechnologies
Abnova provide a range of PEG and Anti-PEG ELISA Kits.
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ELISA
Abnova Corporation
The QuickSwitch™ Quant Tetramer Kit can quantify the exchange with the new peptide for epitope discovery and verify that the resulting new specificity tetramer is suitable for cell staining. This kit is optimised for 10 peptide exchanges and multiple tests per resulting tetramer.
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Tetramers
Medical & Biological Laboratories (MBL)
A reversible T cell exhaustion model for functional screening of immune checkpoint drug candidates.
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Immunology
Medical & Biological Laboratories (MBL)
MBLs p62 and phospho-p62 ELISA Kits come with a lysis buffer, are useful for drug screening and can be used with Human or Mouse cell lysate.
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ELISA
Medical & Biological Laboratories (MBL)
Analyse antigen specific CD8+ T cell responses to SARS-CoV-2 quickly and easily with the MHC class I QuickSwitch™ kits bundled with SARS-CoV-2 peptides.
Documents
Tetramers
Medical & Biological Laboratories (MBL)
The QuickSwitch™ Quant Tetramer Kit for Class II MHCs quantifies the exchange of your peptides of interest for epitope discovery, vaccine design, and immune monitoring. Verify the newly created specificity tetramer for cell staining and functional analysis. This kit is optimized for 10 peptide exchanges and multiple tests per resulting tetramer.
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Tetramers
Medical & Biological Laboratories (MBL)
Find popular targets for antigen specific T-cell detection.
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Proteins
Medical & Biological Laboratories (MBL)
To investigate the immune response to influenza viral infection, MBLI offers MHC Tetramers for detection of T cells specific to common viral influenza antigens.
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Tetramers
Medical & Biological Laboratories (MBL)
MHC tetramers are complexes of four MHC molecules, associated with a specific peptide and bound to a fluorochrome. Class II tetramers bind to a distinct population of CD4+ T cells.
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Tetramers
Medical & Biological Laboratories (MBL)
MBLI offers novel solutions for screening MHC binding peptides and creating custom MHC tetramers.
Documents
Tetramers
Medical & Biological Laboratories (MBL)
A technology allowing quantitative measurement of CD1d-positive NKT cells would be a useful tool for immunology and clinical laboratory examinations. The development of MHC Tetramer technology has provided a breakthrough in the ability to follow T cell populations defined by their antigen specificity.
Documents
Tetramers
Medical & Biological Laboratories (MBL)
CrownVivo™ antibodies are functional grade isotype controls manufactured specifically for in vivo animal studies including antigen neutralization and pathway/blockade depletion assays during the development and validation of antibody biotherapeutics. These isotype controls are designed to avoid cross-reactivity with common preclinical species and are supplied in the exact format needed for in vivo, ex vivo, or in vitro studies.
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Antibodies
Medical & Biological Laboratories (MBL)
Krishgen Biosystems offers a range of ELISA kits for monitoring biotherapies.
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ELISA
Krishgen Biosystems
Krishgen Biosystems offer a range of vaccine titer assays.
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ELISA
Krishgen Biosystems