Welcome to ProSci - Distributed in the UK & Ireland by Caltag Medsystems

ProSci

ProSci a broad catalogue of over 30,000 research antibodies and has completed over 20,000 Custom Antibody projects.

Their in-house labs and animal facilities (USDA licensed and NIH/OLAW approved) provide an extensive array of antibody products & services, with a focus on providing the highest quality monoclonal, polyclonal, and single domain antibodies.

ProSci's expertise in antibody production, immunochemistry services, and biological research is realised through customisable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.

Established in 1998, ProSci is a reliable partner with over 20 years of serving the research community globally.

Offers

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20% off Biosimilars

Get 20% off ProSci's Biosimilar Antibodies until 31st December 2025! Contact us with promo code '2025Biosimilar20CalTag' to redeem this offer.

Antibodies

ProSci specialises in the production of affinity-purified peptide-specific antibodies to novel antigens in fields such as HIV, Apoptosis, Signal Transduction, Neurobiology, Autophagy, and Immunology.

Affinity-purification allows for the isolation of antibodies specific to the epitope of interest. This results in ProSci's polyclonal antibodies having the same specificity as monoclonal antibodies at a competitive price.

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Single Domain Antibodies

ProSci's Single Domain Antibody products are highly valuable in fundamental research, diagnostic, and therapeutic applications.

Single Domain Antibodies (sdAbs), also known as VHH antibodies or nanobodies, are isolated from camelid heavy chain only antibodies and are comprised of only the variable domain. As such, they lack light chains, are smaller and more stable compared to conventional antibodies, yet possess fully functional antigen-binding capability.

Due to their size (approximately 15 kDa) and their longer CDR3 region, a single domain antibody is adept at reaching otherwise inaccessible epitopes that may play a crucial role in the molecular mechanisms of disease.

Single Domain Antibodies - Podcast

Single Domain Antibodies - Video

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Research Grade Biosimilars

Beyond therapeutics, monoclonal antibodies (mAbs) shown to be effective in the clinic can help to facilitate laboratory research.

mAbs, also known as biosimilars, are useful tools to research novel therapies and uncover effective off-target applications.

With known and approved data on toxicity and efficacy, these biologics are used as benchmarks to accelerate findings from bench to clinic.

ProSci has more than 800 research-grade biosimilar antibodies available in the following research areas:

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Recombinant Proteins & Peptides

ProSci's recombinant proteins are available as monomers, dimers, trimers, and multimers.

Full-length and partial-length proteins are available for control experiments, assay development, and antibody development projects.

Utilisation of E. coli, mammalian, yeast, and baculovirus expression systems with various activity assays have been performed to ensure functionality.

Applications of ProSci's recombinant proteins include CLIA, EIA, IM, Lateral Flow, and WB.

As well as recombinant proteins, ProSci also provides peptides. Match one of ProSci's peptides with a primary antibody for blocking and control experiments.

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Research Areas

ProSci also provides products for the following research areas:

Other Products

ProSci also offers a complete assortment of cell & tissue lysates, antibiotics & antimicrobials, isotype controls, and more to complement the use of their antibodies, peptides, and recombinant proteins.

See all ProSci's Other Products

ProSci Custom Antibody Services

High-quality technical assistance, competitive pricing, and highly customisable projects qualify ProSci staff as experts in custom antibody development & production.

The value and convenience of ProSci's custom antibody production services are further advanced with a complete spectrum of available immunochemistry services. These include (but are not limited to) antigen design assistance, peptide synthesis, protein conjugation, and immunisation.

Caltag Medsystems is here with you every step of the way to support your custom antibody project with ProSci.

ProSci custom antibody services include:

ProSci Support

For further ProSci information, please visit prosci-inc.com.

To find informative antibody protocols, downloadable content, and other reference materials, please visit Application & Techniques.

Blog posts

RBD-SpyCatcher-mi3 vaccine construct could be a promising candidate for broad protection against SARS-CoV-2 variants, advocating for further clinical testing.

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ProSci’s Custom Antibody Services were used to develop a mouse monoclonal antibody against cGAMP in a recent study.

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ProSci has generated several antibody reagents for SARS-CoV-2 research. Two of these antibodies were used in research by Yunguang Sun and colleagues.

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At ProSci, custom polyclonal antibodies are generated in various host species from customised immunogens designed by expert antibody scientists.

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ProSci has more than 800 research-grade biosimilar antibodies in their catalogue and a team of custom antibody specialists providing expertise.

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ProSci offers a suite of services to develop rabbit recombinant antibodies with a defined structure, providing highly consistent & specific antibodies.

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ProSci offers reagents that can be used to study the actions of multiple immune checkpoint proteins such as CTLA-4, PD-1, & its ligands PD-L1 & PD-L2.

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To support research & studies into infectious diseases, ProSci has reagents for the study of many viral disease agents inc. Covid, HIV, & Influenza.

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As viruses create more of themselves, they mutate - single-point changes in genetic code. SARS-CoV-2 virus mutated to be more transmissible.

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The cytokine storm is a relatively new discovery & is actively being studied. ProSci offers cytokine & chemokine antibodies & recombinant proteins.

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Research continues in understanding mechanisms of SARS-CoV-2 immune evasion. ProSci offers antibodies & recombinant proteins for SARS-CoV-2 research.

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The SARS-CoV-2 genome is ~29 kb divided into 10 ORFs. Each of these ORFs (except seemingly ORF10) is translated in 29 different proteins.

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ProSci has developed SARS-CoV-2 variant-specific reagents by focusing on unique point mutations in the spike protein.

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mAbs (biosimilars) as tools to research novel new therapies and uncover effective off-target application.

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This white paper details findings in molecular mechanisms that govern necroptosis related to RIPK & details #2283 use to analyse expression of RIPK3.

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ProSci has 25+ years expertise in developing antibodies. This white paper details use of RIPK antibodies & findings on RIPKs in signalling pathways.

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