ReZolve Scientific provides unique imaging solutions which will reduce your preparation and extend your imaging time. The proprietary ReZolveâ„¢ and Ira-Zolveâ„¢ dyes are derived from low-spin transition metal complexes.
Immuno-Oncology (IO) is now providing novel and exciting targeted cancer treatments. The number
of potential immune targets that can be used for immunotherapy continues to grow. ProSci is actively
developing antibodies to aid IO research, diagnostics and therapeutic development.
The B cell-stimulating molecules, BAFF (B cell activating factor also known as BLyS; TALL-1; CD257 or TNFSF13B) and APRIL (a proliferation-inducing ligand, also known as CD256 or TNFSF13), are critical factors in the maintenance of the B cell pool and humoral immunity
Paroxysmal Nocturnal Hemoglobinuria (PNH) is a clonal hematopoietic stem cell (HSC) disease characterized by the continuous destruction of red blood cells. IQP provides Antibodies which specifically detect GPI-anchored proteins on erythrocytes, monocytes and granulocytes, for PNH detection
T-Cell Receptors recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. Biotinylation of MHC/peptide complexes followed by tetramerization with fluorochrome conjugated streptavidin increases their binding affinity. Therefore MHC tetramers bind stably to cognate T-cell receptors and consequently can be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violetâ„¢ 421 (BV421) fluorochromes are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy using our MHC Multimers.
hAD-MSCs are multipotent stem cells, capable of rapid proliferation, trilineage differentiation, and potent
immunomodulation, found in abundance in the stromal vascular fraction of adipose tissue. Currently, adipose tissue is
the most common source of MSCs in clinical use.
Human Articular Chondrocytes (HC-a) are mature cells responsible for elaborating and maintaining cartilage matrices
in vivo. These cells can be difficult to isolate and expand, but have huge potential in translational research. CELLvoâ„¢
Chondrocytes are isolated from cadaveric articular cartilage of otherwise healthy donors in xeno-free conditions. When
grown on the CELLvoâ„¢ Matrix, CELLvoâ„¢ HCs behave more naturally, allowing researchers greater control of their study.
Utilising Gallus' eggspertise, Nordic-MUbio are now able to offer a greatly expanded range of antibodies generated in chicken. Polyclonal Antibodies generated in chickens, offer many advantages over Polyclonal Antibodies traditionally produced in mammals such as rabbits, goats and sheep. Chickens produce immunoglobulin not only in their serum, but also in the egg yolk. The concentration of immunoglobulin measured in egg yolks has been reported to be higher than that found in mammalian and chicken serum. Chickens are more apt to make high-avidity antibodies compared to mammalian antigens.
The benefits of the unique CELLvo Matrix, the only natural cell culture substrate, will be discussed. The webinar describes the current challenges in removing cells from their native tissue and culturing them in a completely foreign environment such as tissue culture plastic. CELLvo Matrix addresses this by providing a 'home' that mimics the native cell derived micro-environment that they came from. It promotes cell adhesion with better isolation and proliferation of primary cells and enhanced cellular responsiveness to experimental variables.
Immunometabolism is a research field that provides new insights into the dynamic cross-talk between the immune system (immunity) and metabolic processes of an organism (metabolism). Immunometabolism tries to understand how metabolism controls the function
of immune cells.
MORE CELLS. SMALLER CELLS. HIGHER SSEA-4 EXPRESSION.
StemBioSys’ naturally produced BM-HPME® allows for rapid and efficient
expansion of stem cells which express biochemical and functional
characteristics indicative of potent cells and a gene expression profile
highlighted by increased expression of anti-inflammatory cytokines.
BM-HPME is an extracellular matrix (ECM) of proteins synthesized in vitro by bone marrow stromal cells. This product is composed of more than 150 proteins that were secreted and assembled by bone marrow cells during the production the HPME