NG 011
Product Code: AG-CN2-0178
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0178-M001 | 1 mg | £130.00 |
Quantity:
| AG-CN2-0178-M005 | 5 mg | £490.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NG-011; BK223B; 15G256alpha1
Appearance:
Off-white solid.
CAS:
141731-75-1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C31H36O15/c1-14-5-18-9-20(32)11-22(34)28(18)31(41)45-17(4)8-25(37) 46-27(39)13-26(38)43-15(2)6-19-10-21(33)12-23(35)29(19)30(40)44-16(3)7-24(36)42-14/h9-12,14-17,27,32-35,39H,5-8,13H2,1-4H3/t14-,15-,16-,17-,27-/m1/s1
InChiKey:
MRSORNRSXAQNPV-VVIQKPQNSA-N
Long Description:
Chemical. CAS: 141731-75-1. Formula: C32H38O15. MW: 662.7. Isolated from Penicillium sp. Antibiotic. Mycotoxin. Very weak cytotoxic activity. Antifungal. Inhibits cell wall biosynthesis. Nerve growth factor (NGF) potentiator.
MDL:
MFCD00910719
Molecular Formula:
C32H38O15
Molecular Weight:
662.7
Package Type:
Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Antibiotic. Mycotoxin. Very weak cytotoxic activity. Antifungal. Inhibits cell wall biosynthesis. Nerve growth factor (NGF) potentiator.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
OC(C=C1O)=CC(C[C@@H](C)OC(C[C@@H](C)O2)=O)=C1C(O[C@H](C)CC(O[C@@H](O)CC(O[C@H](C)CC(C=C(O)C=C3O)=C3C2=O)=O)=O)=O
Solubility Chemicals:
Soluble in methanol, ethanol or DMSO (all 1mg/ml).
Source / Host:
Isolated from Penicillium sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
NG 011 and NG 012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties: M. Ito, et al.; J. Antibiot. 45, 1559 (1992) | NG 011 and NG 012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012: M. Ito, et al.; J. Antibiot. 45, 1566 (1992) | Antifungal macrocyclic polylactones from Penicillium verruculosum: J. Breinholt, et al.; J. Antibiot. 46, 1101 (1993) | Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256: G. Schlingmann, et al.; Tetrahedron 58, 6825 (2002) | Biomimetic Synthesis of Resorcylate Natural Products Utilizing Late Stage Aromatization: Concise Total Syntheses of the Marine Antifungal Agents 15G256iota and 15G256beta: I. Navarro, et al.; JACS 130, 10293 (2008) | New Cytotoxic Metabolites from the Marine-Derived Fungus Penicillium sp. ZLN29: H. Gao, et al.; Helv. Chim. Acta 96, 514 (2013) | New polyesters from Talaromyces flavus: J.-W. He, et al.; Tetrahedron 70, 4425 (2014)