Arbutin
Code | Size | Price |
---|
CDX-A0402-G010 | 10 g | £84.00 |
Quantity:
CDX-A0402-G025 | 25 g | £157.00 |
Quantity:
CDX-A0402-G050 | 50 g | £267.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
+20°C
Images
Documents
Further Information
Alternate Names/Synonyms:
beta-Arbutin; NSC 4036; 4-Hydroxyphenyl-beta-D-glucopyranoside; p-Arbutin; Hydroquinone beta-D-glucopyranoside
Appearance:
Light yellow powder.
CAS:
497-76-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
InChiKey:
BJRNKVDFDLYUGJ-RMPHRYRLSA-N
Long Description:
Chemical. CAS: 497-76-7. Formula: C12H16O7. MW: 272.25. Arbutin is a glycosylated hydroquinone used in traditional Chinese medicine (TCM) that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, anti-tumor and anti-inflammatory properties. Arbutin is a competitive inhibitor of tyrosinase in melanocytes (suppressing production of melanin) and therefore used as a skin-lightening agent and in the treatment of hyperpigmentation disorders.
MDL:
MFCD00016915
Molecular Formula:
C12H16O7
Molecular Weight:
272.25
Package Type:
Vial
Product Description:
Arbutin is a glycosylated hydroquinone used in traditional Chinese medicine (TCM) that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, anti-tumor and anti-inflammatory properties. Arbutin is a competitive inhibitor of tyrosinase in melanocytes (suppressing production of melanin) and therefore used as a skin-lightening agent and in the treatment of hyperpigmentation disorders.
Purity:
>98% (HPLC)
SMILES:
O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC=C(O)C=C2)[C@@H]1O
Solubility Chemicals:
Soluble in DMSO (10mg/ml), ethanol (1mg/ml) or water (25mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
References
(1) K. Maeda & M. Fukuda; JPET 276, 765 (1996) | (2) J. Takebayashi, et al.; Free Radic. Res. 44, 473 (2010) | (3) D.-H. Seo, et al.; Appl. Microbiol. Biotechnol. 95, 1417 (2012) | (4) A. Garcia-Jimenez, et al.; PLoS One 12, e0177330 (2017) | (5) J. Ye, et al.; Pulm. Pharmacol. Ther. 54, 53 (2019)