(-)-Epicatechin gallate

Chemodex
Product Code: CDX-E0181
Supplier: Chemodex
CodeSizePrice
CDX-E0181-M01010 mg£126.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C Long Term: +4°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
ECG; (-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
Appearance:
Light-yellow powder.
CAS:
1257-08-5
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1
InChiKey:
LSHVYAFMTMFKBA-TZIWHRDSSA-N
Long Description:
Chemical. CAS: 1257-08-5. Formula: C22H18O10. MW: 442.37. Isolated from plant source. The catechins (-)-epicatechin (EC) and (-)-epigallocatechin gallate (EGCG) are abundant in green and black teas. (-)-Epicatechin gallate (ECG) is a natural catechin with a single galloyl group. Like EGCG, it inhibits the growth of cancer cells and has anti-inflammatory effects. The hydroxyl groups of ECG contribute to its potent antioxidant activity and facilitate the killing of methicillin-resistant strains of S. aureus.
MDL:
MFCD00075936
Molecular Formula:
C22H18O10
Molecular Weight:
442.37
Package Type:
Vial
Product Description:
The catechins (-)-epicatechin (EC) and (-)-epigallocatechin gallate (EGCG) are abundant in green and black teas. (-)-Epicatechin gallate (ECG) is a natural catechin with a single galloyl group. Like EGCG, it inhibits the growth of cancer cells and has anti-inflammatory effects. The hydroxyl groups of ECG contribute to its potent antioxidant activity and facilitate the killing of methicillin-resistant strains of S. aureus.
Purity:
>98% (HPLC)
SMILES:
OC1=C(C[C@@H](OC(C2=CC(O)=C(O)C(O)=C2)=O)[C@@H](C3=CC=C(O)C(O)=C3)O4)C4=CC(O)=C1
Solubility Chemicals:
Soluble in water, acetone, DMSO (10mg/ml), methanol, ethanol (1mg/ml) or DMF (10mg/ml).
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) J.Z. Xu, et al.; Br. J. Nutr. 91, 873 (2004) | (2) M.H. Ravindranath, et al.; Evidence-Based Compl. Altern. Med. 6, 523 (2009) | (3) C. Kuerbitz, et al.; Cancer Sci. 102, 728 (2011) | (4) J.C. Anderson, et al.; Bioorg. Med. Chem. Lett. 21, 6996 (2011) | (5) G.J. Du, et al.; Nutrients 4, 1679 (2012)