Isoorientin
| Code | Size | Price |
|---|
| CDX-I0095-M001 | 1 mg | £59.00 |
Quantity:
| CDX-I0095-M005 | 5 mg | £102.00 |
Quantity:
| CDX-I0095-M010 | 10 mg | £175.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C, Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
Homoorientin; Luteolin 6-C-beta-D-glucoside; Luteolin 6-C-glucoside; Lespecapitioside
Appearance:
Yellow powder.
CAS:
4261-42-1
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14-,17-,19+,20-,21+/m1/s1
InChiKey:
ODBRNZZJSYPIDI-VJXVFPJBSA-N
Long Description:
Chemical. CAS: 4261-42-1. Formula: C21H20O11. MW: 448.38. Isolated from plant source. Isoorientin is a flavonoid with various biological properties. It has anticancer, antioxidant, anti-inflammatory, antimicrobial, gastroprotective and antinociceptive activities. It induces apoptosis in and reduces cell viability of cancer cells. It is a selective Cyclooxygenase-2 (COX-2) inhibitor. Reduces expression of COX-2, IL-6, 5-lipoxygenase (5-LO), and TNF-alpha in RAW 264.7 cells. It also has shown to regulate lipid metabolism.
MDL:
MFCD00017433
Molecular Formula:
C21H20O11
Molecular Weight:
448.38
Package Type:
Vial
Product Description:
Isoorientin is a flavonoid with various biological properties. It has anticancer, antioxidant, anti-inflammatory, antimicrobial, gastroprotective and antinociceptive activities. It induces apoptosis in and reduces cell viability of cancer cells. It is a selective Cyclooxygenase-2 (COX-2) inhibitor. Reduces expression of COX-2, IL-6, 5-lipoxygenase (5-LO), and TNF-alpha in RAW 264.7 cells. It also has shown to regulate lipid metabolism.
Purity:
>98% (HPLC)
SMILES:
OC(C(C(C=C(C1=CC(O)=C(O)C=C1)O2)=O)=C2C=C3O)=C3[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4
Solubility Chemicals:
Soluble in DMSO (15mg/ml), DMF (15mg/ml) or methanol (5mg/ml).
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) M. Sumalatha, et al.; Nat. Prod. Commun. 10, 1703 (2015) | (2) L. Yuan, et al.; J. Agric. Food Chem. 64, 2682 (2016) | (3) X. Lin, et al.; J. Ethnopharmacol. 187, 187 (2016) | (4) L. Yuan, et al.; Biomed. Pharmacother. 81, 356 (2016) | (5) T. Ye, et al.; Onco. Targets Ther. 9, 7481 (2016) | (6) K. Anilkumar, et al.; Oxid. Med. Cell. Longev. 2017, 5498054 (2017) | (7) E.S. Karaoglan, et al.; Acta. Cir. Bras. 33, 609 (2018) | (8) L. Yuan, et al.; J. Agric. Food Chem. 66, 9777 (2018) | (9) G. Zhang, et al.; Int. Immunopharmacol. 75, 105753 (2019)