Cnidicin
| Code | Size | Price |
|---|
| CDX-C0728-M001 | 1 mg | £121.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +4°C Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
Kinidilin; Knidicin; 4,9-bis(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
Appearance:
Light yellow powder.
CAS:
14348-21-1
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C21H22O5/c1-13(2)7-10-23-18-15-5-6-17(22)26-20(15)21(25-11-8-14(3)4)19-16(18)9-12-24-19/h5-9,12H,10-11H2,1-4H3
InChiKey:
HJMDOAWWVCOEDW-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 14348-21-1. Formula: C21H22O5. MW: 354.4. Cnidicin is a natural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).
MDL:
MFCD32197347
Molecular Formula:
C21H22O5
Molecular Weight:
354.4
Package Type:
Vial
Product Description:
Cnidicin is a natural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).
Purity:
>98% (HPLC)
SMILES:
C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) S.Y. Ryu, et al.; Planta Med. 67, 172 (2001) | (2) Y.K. Kim, et al.; Phytother. Res. 21, 288 (2007)