RN486

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TargetMol
Product Code: TAR-T1976
Supplier: TargetMol
CodeSizePrice
TAR-T1976-1mg1mg£132.00
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TAR-T1976-5mg5mg£155.00
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TAR-T1976-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T1976-10mg10mg£209.00
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TAR-T1976-25mg25mg£349.00
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TAR-T1976-50mg50mg£511.00
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TAR-T1976-100mg100mg£736.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).
CAS:
1242156-23-5
Formula:
C35H35FN6O3
Molecular Weight:
606.702
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9938
SMILES:
CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)nc1
Target:
BTK

References

1. Xu D, et al. J Pharmacol Exp Ther, 2012, 341(1), 90-103.