Mepyramine
Code | Size | Price |
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TAR-T24451-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-1mL | 1 mL * 10 mM (in DMSO) | £326.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-5mg | 5mg | £340.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-10mg | 10mg | £470.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-25mg | 25mg | £707.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-50mg | 50mg | £978.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24451-100mg | 100mg | £1,291.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
CAS:
91-84-9
Formula:
C17H23N3O
Molecular Weight:
285.39
Purity:
0.9907
SMILES:
CN(C)CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=C2
References
1. Jain S, Panyutin A, Liu N, Xiao C, Pi?ol RA, Pundir P, Girardet C, Butler AA, Dong X, Gavrilova O, Reitman ML. Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. Am J Physiol Endocrinol Metab. 2018 May 29. doi: 10.1152/ajpendo.00024.2018. [Epub ahead of print] PubMed PMID: 29812984.
2. Alachkar A, Latacz G, Siwek A, Lubelska A, Honkisz E, Grybo? A, ?a?ewska D, Handzlik J, Stark H, Kiec-Kononowicz K, Sadek B. Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats. Pharmacol Biochem Behav. 2018 May 3;170:14-24. doi: 10.1016/j.pbb.2018.04.010. [Epub ahead of print] PubMed PMID: 29729290.
3. Kennedy L, Hargrove L, Demieville J, Karstens A, Jones H, DeMorrow S, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Smith S, Akers A, Meadows V, Francis H. Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2(-/-) mice and human cholangiocarcinoma tumorigenesis. Hepatology. 2018 Mar 30. doi: 10.1002/hep.29898. [Epub ahead of print] PubMed PMID: 29601088.
4. Popiolek-Barczyk K, ?a?ewska D, Latacz G, Olejarz A, Makuch W, Stark H, Kie?-Kononowicz K, Mika J. Antinociceptive effects of novel histamine H(3) R and H(4) R receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse. Br J Pharmacol. 2018 Feb 27. doi: 10.1111/bph.14185. [Epub ahead of print] PubMed PMID: 29486058.