Euphorbia factor L1
| Code | Size | Price |
|---|
| TAR-T2S0410-1mL | 1 mL * 10 mM (in DMSO) | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T2S0410-20mg | 20mg | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1. Euphorbia factor L1 can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. 2. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level.
CAS:
76376-43-7
Formula:
C32H40O8
Molecular Weight:
552.664
Pathway:
Membrane transporter/Ion channel; Apoptosis; Neuroscience
Purity:
0.98
SMILES:
C[C@H]1C[C@@]2(OC(C)=O)[C@H]([C@H]1OC(=O)Cc1ccccc1)[C@@H](OC(C)=O)[C@@]1(CO1)CC[C@H]1[C@@H](C=C(C)C2=O)C1(C)C
Target:
Apoptosis; P-gp
References
1. Park SJ, et al. Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells via activation of AMP-activated protein kinase.Cell Biochem Funct. 2015, 33(4):220-5.
2. Jung Sook Choi, et al. Euphorbiasteroid reverses P?glycoprotein?mediated multi?drug resistance in human sarcoma cell line MES?SA/Dx5.Phytotherapy research. 2010, 24(7):1042-1046.