SIRT7 inhibitor 97491

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TargetMol
Product Code: TAR-T39233
Supplier: TargetMol
CodeSizePrice
TAR-T39233-1mg1mg£148.00
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TAR-T39233-5mg5mg£269.00
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TAR-T39233-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T39233-10mg10mg£369.00
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TAR-T39233-25mg25mg£576.00
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TAR-T39233-50mg50mg£790.00
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TAR-T39233-100mg100mg£1,050.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
CAS:
1807758-81-1
Formula:
C15H12ClN3O
Molecular Weight:
285.73
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.98
SMILES:
Nc1cccc(Nc2ncc(-c(cc3)ccc3Cl)o2)c1
Target:
Sirtuin

References

Ji-Hye Kim, et al. Identification of a Novel SIRT7 Inhibitor as Anticancer Drug Candidate. Biochem Biophys Res Commun. 2019 Jan 8;508(2):451-457.