Aurantio-obtusin

TargetMol
Product Code: TAR-T6S1559
Supplier: TargetMol
CodeSizePrice
TAR-T6S1559-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T6S1559-20mg20mg£151.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. 2. Aurantio-obtusin, stimulated chemotactic migration of MC3T3-E1 osteoblast cells in a concentration-dependent manner. Besides migration, the compound stimulated osteoblast differentiation and mineralization. 3. Aurantio-obtusin is a promising osteoanabolic compound of natural origin with potential therapeutic applications in the prevention of osteoporosis and other metabolic bone diseases.
CAS:
67979-25-3
Formula:
C17H14O7
Molecular Weight:
330.292
Purity:
0.9805
SMILES:
COc1c(O)cc2C(=O)c3cc(C)c(O)c(OC)c3C(=O)c2c1O

References

Vishnuprasad C N , Tsuchiya T , Kanegasaki S , et al. Aurantio-obtusin stimulates chemotactic migration and differentiation of MC3T3-E1 osteoblast cells.[J]. Planta Medica, 2014, 80(07):544-549.