Gambogenic acid
Code | Size | Price |
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TAR-T8201-1mg | 1mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-5mg | 5mg | £246.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-1mL | 1 mL * 10 mM (in DMSO) | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-10mg | 10mg | £374.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-25mg | 25mg | £571.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-50mg | 50mg | £779.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8201-100mg | 100mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.
CAS:
173932-75-7
Formula:
C38H46O8
Molecular Weight:
630.778
Pathway:
Chromatin/Epigenetic
Purity:
0.9836
SMILES:
[H][C@@]12C[C@H]3C=C4C(=O)c5c(O)c(CC=C(/C)CCC=C(C)C)c(O)c(CC=C(C)C)c5O[C@@]14[C@@](CC=C(C)C(O)=O)(OC2(C)C)C3=O
Target:
Histone Methyltransferase
References
Wang X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017 May 2;36(9):1243-1260.
Wu J, Wang D, Zhou J, et al. Gambogenic acid induces apoptosis and autophagy through ROS?mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells. Phytotherapy Research. 2022;1?19.