BI-0115

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TargetMol
Product Code: TAR-T9108
Supplier: TargetMol
CodeSizePrice
TAR-T9108-1mg1mg£160.00
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TAR-T9108-5mg5mg£262.00
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Quantity:
TAR-T9108-10mg10mg£356.00
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Quantity:
TAR-T9108-25mg25mg£544.00
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Quantity:
TAR-T9108-50mg50mg£760.00
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Quantity:
TAR-T9108-100mg100mg£1,018.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.
CAS:
4929-23-1
Formula:
C15H14ClN3O
Molecular Weight:
287.75
Pathway:
Metabolism
Purity:
0.9969
SMILES:
CCCN1c2cccnc2Nc2cc(Cl)ccc2C1=O
Target:
Lipoxygenase