Cucurbitacin D
Code | Size | Price |
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TAR-TN1013-10mg | 10mg | £255.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN1013-1mL | 1 mL * 10 mM (in DMSO) | £263.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.
CAS:
3877-86-9
Formula:
C30H44O7
Molecular Weight:
516.675
Pathway:
JAK/STAT signaling; Immunology/Inflammation; MAPK; Stem Cells
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)C=CC(C)(C)O)[C@@]3(C)CC(=O)[C@@]21C
Target:
IL Receptor; JNK; STAT
References
Cucurbitacin D is a new inflammasome activator in macrophages.Int Immunopharmacol. 2013 Dec;17(4):1044-50.