alpha-Viniferin
| Code | Size | Price |
|---|
| TAR-TN1378-5mg | 5mg | £337.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN1378-1mL | 1 mL * 10 mM (in DMSO) | £1,556.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Alpha-viniferin is a prostaglandin H2 synthase inhibitor, which has anti-inflammatory, anti-oxidant, anti-arthritis, and anti-tumor activities.
CAS:
62218-13-7
Formula:
C42H30O9
Molecular Weight:
678.693
Pathway:
GPCR/G Protein; Metabolism; Immunology/Inflammation;
Purity:
0.98
SMILES:
[H][C@]12[C@@H](Oc3cc(O)cc(c13)[C@]1([H])[C@H](Oc3cc(O)cc(c13)[C@@]1([H])[C@@H](Oc3cc(O)cc2c13)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1
Target:
P45; Prostaglandin Receptor
References
Lee JY, et al. alpha-Viniferin suppresses the signal transducer and activation of transcription-1 (STAT-1)-inducible inflammatory genes in interferon-gamma-stimulated macrophages.J Pharmacol Sci. 2010;112(4):405-14.
Fan Y, et al. Pharmacokinetic and bioavailability studies of ?-viniferin after intravenous and oral administration to rats. J Pharm Biomed Anal. 2020 Sep 5;188:113376.
Sim J, et al. Potent inhibitory effect of alpha-viniferin on human cytochrome P450. Food Chem Toxicol. 2014 Jul;69:276-80.
Seo H, et al. In vitro activity of alpha-viniferin isolated from the roots of Carex humilis against Mycobacterium tuberculosis. Pulm Pharmacol Ther. 2017 Oct;46:41-47.