Citreorosein
| Code | Size | Price |
|---|
| TAR-TN1504-5mg | 5mg | £914.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN1504-1mL | 1 mL * 10 mM (in DMSO) | £1,113.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
CAS:
481-73-2
Formula:
C15H10O6
Molecular Weight:
286.239
Pathway:
PI3K/Akt/mTOR signaling; NF-κb; GPCR/G Protein
Purity:
0.98
SMILES:
OCc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Target:
cAMP; NF-κB; PI3K
References
Citreorosein inhibits degranulation and leukotriene C₄ generation through suppression of Syk pathway in mast cells.Mol Cell Biochem. 2012 Jun;365(1-2):333-41.