Ganoderic acid C1
| Code | Size | Price |
|---|
| TAR-TN1660-1mg | 1mg | £159.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN1660-5mg | 5mg | £496.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α? mediated inflammation in asthma and other inflammatory diseases. Ganoderic acid C1 has anti-tumor-promoting activity. It is moderately active inhibitors against HIV-1 protease.
CAS:
95311-97-0
Formula:
C30H42O7
Molecular Weight:
514.659
Pathway:
Neuroscience; DNA Damage/DNA Repair; Cell Cycle/Checkpoint; MAPK; NF-κb; Microbiology/Virology; Proteases/Proteasome; Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](O)C3=C(C(=O)C[C@]4(C)[C@H](CC(=O)[C@@]34C)[C@H](C)CC(=O)C[C@@H](C)C(O)=O)[C@@]1(C)CCC(=O)C2(C)C
Target:
IL Receptor; TNF; NF-κB; MAPK; COX; HIV Protease; DNA/RNA Synthesis
References
Liu C, et al. Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-?B Signaling. Inflamm Bowel Dis. 2015 Aug;21(8):1918-25.
Changda Liu, et al. Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI? suppresses TNF-? production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. Int Immunopharmacol. 2015 Aug;27(2):224-31.