Tetrahydroalstonine
| Code | Size | Price |
|---|
| TAR-TN2267-1mL | 1 mL * 10 mM (in DMSO) | £426.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN2267-5mg | 5mg | £528.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tetrahydroalstonine and Raubasine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, respectively.
CAS:
6474-90-4
Formula:
C21H24N2O3
Molecular Weight:
352.434
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
[H][C@@]12C[C@]3([H])C(=CO[C@@H](C)[C@]3([H])CN1CCc1c2[nH]c2ccccc12)C(=O)OC
Target:
Adrenergic Receptor
References
Liao Y, et al. The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation. Molecules. 2023 ; 28(5):2370.
Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 ; 106(1):203-205.
Roquebert J, et al. Differential inhibition of raubasine and tetrahydroalstonine on the vasopressor response to sympathetic nervous stimulation and intravenous noradrenaline in the pithed rat. J Pharmacol. 1985 ; 16(4):412-420.
Malik S. Tetrahydroalstonine from Fruits of Rhazya stricta. Planta Med. 1984 ; 50(3):283.