Anatabine
| Code | Size | Price |
|---|
| TAR-TN3410-5mg | 5mg | £535.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN3410-1mL | 1 mL * 10 mM (in DMSO) | £631.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in human neuronal like SHSY-5Y cells suggesting that the Aβ lowering properties of anatabine are mediated via a regulation of BACE-1 expression.
CAS:
581-49-7
Formula:
C10H12N2
Molecular Weight:
160.22
Pathway:
NF-κb; JAK/STAT signaling; Apoptosis; Neuroscience; Immunology/Inflammation; Stem Cells
Purity:
0.98
SMILES:
C1N[C@@H](CC=C1)c1cccnc1
Target:
Beta Amyloid; IL Receptor; TNF; NF-κB; BACE; COX; STAT