Cearoin
| Code | Size | Price |
|---|
| TAR-TN3614-5mg | 5mg | £491.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN3614-1mL | 1 mL * 10 mM (in DMSO) | £512.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of TNFα and CCL2. Cearoin induces autophagy, ERK activation and apoptosis in neuroblastoma SH-SY5Y cells, which is mediated primarily by ROS generation, suggesting its therapeutic application for the treatment of neuroblastomas.
CAS:
52811-37-7
Formula:
C14H12O4
Molecular Weight:
244.24
Pathway:
Proteases/Proteasome; NF-κb; Chromatin/Epigenetic; MAPK; DNA Damage/DNA Repair; Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
COc1cc(O)c(cc1O)C(=O)c1ccccc1
Target:
ERK; BCL; PARP; IκB/IKK; TNF; NF-κB; ROS; Caspase