Ergosta-7,22-dien-3-one

TargetMol
Product Code: TAR-TN3983
Supplier: TargetMol
CodeSizePrice
TAR-TN3983-5mg5mg£1,009.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN3983-1mL1 mL * 10 mM (in DMSO)£1,201.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
Ergosta-7,22-dien-3-one shows pro-inflammatory property, it can stimulate nitric oxide production, induce the expression of genes, and induce the production of TLRs, cytokines, chemokines, and cellular adhesion molecules in J774A.1 cells.
CAS:
32507-77-0
Formula:
C28H44O
Molecular Weight:
396.65
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
CC(C)[C@@H](C)C=C[C@@H](C)[C@H]1CC[C@H]2C3=CCC4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
LTR

References

Gao J, et al. Cytotoxic constituents of Lasiosphaera fenzlii on different cell lines and the synergistic effects with paclitaxel. Nat Prod Res. 2016;30(16):1862-1865. Ramos-Ligonio A, et al. In Vitro Expression of Toll-Like Receptors and Proinflammatory Molecules Induced by Ergosta- 7,22-Dien-3-One Isolated from a Wild Mexican Strain of Ganoderma oerstedii (Agaricomycetes). Int J Med Mushrooms. 2017;19(3):203-211. Ko HH, et al. Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae. Phytochemistry. 2008;69(1):234-239.