Kaerophyllin
| Code | Size | Price |
|---|
| TAR-TN4374-5mg | 5mg | £1,434.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN4374-1mL | 1 mL * 10 mM (in DMSO) | £1,707.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.
CAS:
75590-33-9
Formula:
C21H20O6
Molecular Weight:
368.4
Pathway:
MAPK; Metabolism; PI3K/Akt/mTOR signaling; Apoptosis; NF-κb; Immunology/Inflammation; DNA Damage/DNA Repair; Cytoskeletal Signaling
Purity:
0.98
SMILES:
COc1ccc(C=C2/[C@@H](Cc3ccc4OCOc4c3)COC2=O)cc1OC
Target:
ERK; IL Receptor; TNF; NF-κB; Akt; PPAR