Nyasol
| Code | Size | Price |
|---|
| TAR-TN4683-5mg | 5mg | £1,508.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN4683-1mL | 1 mL * 10 mM (in DMSO) | £1,836.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly effective in suppressing the Phytophthora blight on pepper plants. (-)-Nyasol exhibits the half maximal inhibitory concentration (IC50) value of 17.6 uM against D-glycero-α-D-manno-heptose-1-phosphate guanylyltransferase (HddC). (+)-Nyasol has antiprotozoal activity, it potently inhibits the growth of Leishmania major promastigotes, the IC50 being 12 microM, and moderately inhibits Plasmodium falciparum schizonts with the IC50 49 microM.
CAS:
96895-25-9
Formula:
C17H16O2
Molecular Weight:
252.31
Pathway:
NF-κb; Cytoskeletal Signaling; Microbiology/Virology; Immunology/Inflammation; PI3K/Akt/mTOR signaling; MAPK
Purity:
0.98
SMILES:
Oc1ccc(C=C/[C@@H](C=C)c2ccc(O)cc2)cc1
Target:
ERK; IL Receptor; IκB/IKK; NOS; NF-κB; Akt; Antifection