(-)-Praeruptorin A

TargetMol
Product Code: TAR-TN4819
Supplier: TargetMol
CodeSizePrice
TAR-TN4819-5mg5mg£328.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN4819-1mL1 mL * 10 mM (in DMSO)£336.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs.
CAS:
14017-71-1
Formula:
C21H22O7
Molecular Weight:
386.39
Pathway:
Immunology/Inflammation; Metabolism; Neuroscience; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CC=C(C)C(=O)O[C@@H]1[C@H](OC(C)=O)c2c(OC1(C)C)ccc1ccc(=O)oc21
Target:
ATPase; IL Receptor; Calcium Channel; P-gp