Siegeskaurolic acid
| Code | Size | Price |
|---|
| TAR-TN5019-1mg | 1mg | £593.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation.
CAS:
52645-97-3
Formula:
C20H32O3
Molecular Weight:
320.47
Pathway:
Neuroscience; GPCR/G Protein; NF-κb; Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
C[C@@]12CCC[C@](C)([C@H]1CC[C@@]13C[C@@H](CO)[C@@H](C1)CC[C@@H]23)C(O)=O
Target:
TNF; NOS; NF-κB; COX; Prostaglandin Receptor
References
Park HJ, et al. Anti-inflammatory activities of ent-16alphaH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation. Eur J Pharmacol. 2007 Mar 8;558(1-3):185-93.