3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone
| Code | Size | Price |
|---|
| TAR-TN5133-5mg | 5mg | £568.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN5133-1mL | 1 mL * 10 mM (in DMSO) | £577.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (?Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.
CAS:
125537-92-0
Formula:
C17H14O8
Molecular Weight:
346.3
Pathway:
Proteases/Proteasome; Microbiology/Virology; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
COc1c(O)cc(cc1O)-c1cc(=O)c2c(O)c(OC)c(O)cc2o1
Target:
HIV Protease; Topoisomerase