(-)-Variabilin

TargetMol
Product Code: TAR-TN5221
Supplier: TargetMol
CodeSizePrice
TAR-TN5221-5mg5mg£512.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN5221-1mL1 mL * 10 mM (in DMSO)£528.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro and shows anti-inflammatory activity after topical or p.o. administration to mice.
CAS:
370102-93-5
Formula:
C17H16O5
Molecular Weight:
300.3
Purity:
0.98
SMILES:
COc1ccc2c(O[C@H]3c4ccc(OC)cc4OC[C@]23O)c1