Hemopressin(rat)
| Code | Size | Price |
|---|
| TAR-TP1901-1mg | 1mg | £291.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. Ki values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB1 receptor inverse agonist. Displays antinociceptive activity and induces hypophagia in vivo.
CAS:
568588-77-2
Formula:
C53H77N13O12
Molecular Weight:
1088.27
Purity:
0.98
SMILES:
0
References
Rioli et al (2003) Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J.Biol.Chem. 278 8547 PMID:
Heimann et al (2007) Hemopressin is an inverse agonist of CB1 cannabinoid receptors. Proc.Natl.Acad.Sci.U.S.A. 104 20588 PMID:
Todd et al (2010) The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice. J.Neurosci. 30 7369 PMID: