[Arg14,Lys15]Nociceptin
| Code | Size | Price |
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| TAR-TP1986-1mg | 1mg | £230.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than nociceptin in vivo; pronociceptive and inhibits locomotor activity.
CAS:
236098-40-1
Formula:
C82H137N31O22
Molecular Weight:
1909.18
Purity:
0.98
SMILES:
0
References
Okada et al (2000) Highly potent nociceptin analog containing the Arg-Lys triple repeat. Biochem.Biophys.Res.Commun. 278 493 PMID:
Calo et al (2002) Pharmacological profile of nociceptin/orphanin FQ receptors. Clin.Exp.Pharmacol.Physiol. 29 223 PMID:
Rizzi et al (2002) [Arg14,Lys15]Nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: in vitro and in vivo studies. J.Pharmacol.Exp.Ther. 300 57 PMID: