NGP555

TargetMol
Product Code: TAR-T16294
Supplier: TargetMol
CodeSizePrice
TAR-T16294-1mg1mg£128.00
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TAR-T16294-2mg2mg£152.00
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TAR-T16294-5mg5mg£229.00
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TAR-T16294-1mL1 mL * 10 mM (in DMSO)£243.00
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TAR-T16294-10mg10mg£318.00
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TAR-T16294-25mg25mg£487.00
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TAR-T16294-50mg50mg£675.00
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TAR-T16294-100mg100mg£922.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
NGP555 is a modulator of γ-secretase.
CAS:
1304630-27-0
Formula:
C23H23FN4S
Molecular Weight:
406.52
Pathway:
Stem Cells; Neuroscience; Proteases/Proteasome
Purity:
0.9977
SMILES:
CCc1cc(Nc2nc(cs2)-c2ccc(c(F)c2)-n2cnc(C)c2)c(C)cc1C
Target:
Gamma-secretase

References

1. Kounnas MZ, et al. NGP 555, a ?-Secretase Modulator, Lowers the Amyloid Biomarker, A?42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents. Alzheimers Dement (N Y). 2017 Jan;3(1):65-73.