Filgotinib

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TargetMol
Product Code: TAR-T1929
Supplier: TargetMol
CodeSizePrice
TAR-T1929-2mg2mg£111.00
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TAR-T1929-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T1929-5mg5mg£128.00
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TAR-T1929-10mg10mg£160.00
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TAR-T1929-25mg25mg£204.00
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TAR-T1929-50mg50mg£322.00
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TAR-T1929-100mg100mg£483.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GLPG0634(filgotinib) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
CAS:
1206161-97-8
Formula:
C21H23N5O3S
Molecular Weight:
425.51
Pathway:
Angiogenesis; Stem Cells; JAK/STAT signaling; Tyrosine Kinase/Adaptors; Chromatin/Epigenetic
Purity:
0.9909
SMILES:
O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
Target:
Tyrosine Kinases; JAK

References

1. Van Rompaey L, et al. J Immunol. 2013, 191(7), 3568-3577.