Ixazomib

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TargetMol
Product Code: TAR-T2122
Supplier: TargetMol
CodeSizePrice
TAR-T2122-1mg1mg£103.00
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TAR-T2122-5mg5mg£148.00
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TAR-T2122-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T2122-10mg10mg£174.00
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TAR-T2122-25mg25mg£306.00
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TAR-T2122-50mg50mg£466.00
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TAR-T2122-100mg100mg£623.00
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TAR-T2122-500mg500mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites (IC50: 31/3500 nM).
CAS:
1072833-77-2
Formula:
C14H19BCl2N2O4
Molecular Weight:
361.03
Pathway:
Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination
Purity:
0.9818
SMILES:
CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O
Target:
Proteasome; Caspase; Autophagy

References

1. Kupperman E, et al. Cancer Res, 2010, 70(5), 1970-80 2. Lee EC, et al. Clin Cancer Res, 2011, 17(23), 7313-23.