NVP-TAE 684

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TargetMol
Product Code: TAR-T2251
Supplier: TargetMol
CodeSizePrice
TAR-T2251-2mg2mg£111.00
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TAR-T2251-5mg5mg£136.00
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TAR-T2251-1mL1 mL * 10 mM (in DMSO)£166.00
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TAR-T2251-10mg10mg£172.00
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TAR-T2251-25mg25mg£253.00
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TAR-T2251-50mg50mg£345.00
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TAR-T2251-100mg100mg£461.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM).
CAS:
761439-42-3
Formula:
C30H40ClN7O3S
Molecular Weight:
614.21
Pathway:
Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Purity:
0.9991
SMILES:
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CCN(C)CC1
Target:
Apoptosis; ALK

References

1. Galkin AV, et al. Proc Natl Acad Sci U S A, 2007, 104(1), 270-275. 2. Katayama R, et al. Proc Natl Acad Sci U S A, 2011, 108(18), 7535-7540. 3. Sch?nherr C, et al, Biochem J, 2011, 440(3), 405-413.